High Content Screening Analysis

Assessing a vast number of compounds is time consuming therefore acquiring a large number of high resolution cellular images with fast scanning speed is critically important for drug screening.

High content screening analysis.

High content screening hcs also known as high content analysis hca or cellomics is a method that is used in biological research and drug discovery to identify substances such as small molecules peptides or rnai that alter the phenotype of a cell in a desired manner. The hypercyt high throughput ht flow cytometry sampling platform uses a peristaltic pump in combination with an autosampler and a novel approach to data collection to circumvent time delay bottlenecks of conventional flow cytometry. High content analysis hca high content analysis is a principle methodology for so called phenotypic screening in drug discovery and development process. High content analysis hca or high content screening hcs combines high throughput automated imaging and analysis to extract quantitative multi parametric data at the single cell level.

Originally developed as a complementary technology to traditional biochemical high throughput screening hts in drug discovery today high content screening. Hence high content screening is a type of phenotypic screen conducted in cells involving the analysis of whole cells or. With an unprecedented flatness whole plate and intra well these microplates are ideal for high resolution cellular imaging applications. This approach also dramatically reduces the amount of sample aspirated for each analysis typically requiring 2 μl per sample while making.